InnateDB Protein
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IDBP-765483.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GPR77
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Protein Name
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000472620
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InnateDB Gene
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IDBG-59470 (GPR77)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0006935
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chemotaxis
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GO:0006954
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inflammatory response
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GO:0007186
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G-protein coupled receptor signaling pathway
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GO:0032720
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negative regulation of tumor necrosis factor production
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GO:0045087
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innate immune response (InnateDB)
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GO:0050679
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positive regulation of epithelial cell proliferation
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GO:0070374
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positive regulation of ERK1 and ERK2 cascade
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GO:0090024
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negative regulation of neutrophil chemotaxis
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GO:1900165
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negative regulation of interleukin-6 secretion
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GO:2000482
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regulation of interleukin-8 secretion
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Cellular Component |
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PDB ID |
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InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like
IPR001274
C5a1/C5a2 anaphylatoxin chemotactic receptor
IPR017452
GPCR, rhodopsin-like, 7TM
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PFAM |
PF00001
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PRINTS |
PR00237
PR00426
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9P296
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PhosphoSite |
PhosphoSite-Q9P296
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
27202
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UniGene |
Hs.534412
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RefSeq |
NP_001258678
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HUGO |
HGNC:4527
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OMIM |
609949
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CCDS |
CCDS12699
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HPRD |
17072
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IMGT |
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EMBL |
AB038237
AC008754
AF317655
AK313994
AY268430
BC067478
CH471126
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GenPept |
AAH67478
AAK12640
AAP23197
BAA95414
BAG36706
EAW57472
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